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Prognostic value of 8-hydroxy-2-deoxyguanosine and human neutrophil elastase/1-proteinase inhibitor complex as salivary biomarkers of oxidative stress in chronic periodontitis

Traditionally, NDD pathogenesis has been viewed through a neurocentric lens focusing on protein misfolding, synaptic dysfunction, and central immune activation [3]

When cortisol rises, T4-to-T3 conversion is suppressed by up to 20 percent , reverse T3 (rT3, the inactive form) rises, and cellular hypothyroidism develops

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10.1016/j.jchemneu.2013.01.001 J

However, suggesting that free GSH, GSSG, and their relative ratio is less valid than total GSH, we found the level of free GSH to be reduced (Fig